Spoilers please.
SPOILERS!Wilson leaves the hospital, initially claiming it's due to remembering Amber too much. End of episode, House apologizes, even though he didn't kill her. Wilson says he doesn't blame him. House asks if they're okay. Wilson says "No" and that he was protecting him from the truth. Wilson's leaving the hospital because of House, after finally having had enough of their "friendship". The lines I distinctly remember are:
"You spread misery because you can't feel anything else. You manipulate people because you can't handle any kind of real relationship."
"If I've learned anything from Amber, it's that I have to take care of myself. We're not friends anymore, House. I'm not sure we ever were."